| Product Name |
6-carboxytetrahydropterin synthase |
| Example Structure |
 |
| Synonyms |
6-carboxy-5,6,7,8-tetrahydropterin synthase, 6-pyruvoyltetrahydropterin synthase, CPH4 synthase, PTPS, QueD |
| EC Number |
4.1.2.50 |
| CAS Registry Number |
|
| Comments |
Binds Zn2+. Isolated from the bacteria?Bacillus subtilis?and?Escherichia coli. The reaction is part of the biosynthesis pathway of queuosine. The enzyme from?Escherichia coli?can also convert 6-pyruvoyl-5,6,7,8-tetrahydropterin and sepiapterin to 6-carboxy-5,6,7,8-tetrahydropterin [1]. |
| Cofactor |
Zn2+ |
| History |
|
| Reactions |
7,8-dihydroneopterin 3′-triphosphate + H(2)O = 6-carboxy-5,6,7,8- tetrahydropterin + acetaldehyde + triphosphate. |
