6-hydroxy-3-succinoylpyridine 3-monooxygenase EC#: 1.14.13.163; ChemWhat Code: 1375400
| Product Name | 6-hydroxy-3-succinoylpyridine 3-monooxygenase |
| Example Structure |  |
| Synonyms | 6-hydroxy-3-succinoyl-pyridine 3-monooxygenase, 6-hydroxy-3-succinoylpyridine hydroxylase, AWN88_01205, Hsh, HSP 3-monooxygenase, HSP hydroxylase, hspA, hspB, HSPH, HSPHZZ, NADH-dependent HSP hydroxylase, NIC, nicotine hydroxylase, VppD |
| EC Number | 1.14.13.163 |
| CAS Registry Number | |
| Comments | The enzyme catalyses a reaction in the nicotine degradation pathway of Pseudomonas species. One of the enzymes from the soil bacterium Pseudomonas putida S16 contains an FAD cofactor [2]. |
| Cofactor | FAD |
| History | |
| Reactions | 4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + 2 Nadh + O(2) = 2,5- dihydroxypyridine + succinate semialdehyde + 2 NAD(+) + H(2)O. |
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