7,8-dihydroneopterin 2′,3′-cyclic phosphate phosphodiesterase EC#: 3.1.4.56; ChemWhat Code: 1379637

Product Name 7,8-dihydroneopterin 2′,3′-cyclic phosphate phosphodiesterase
Example Structure Example Structure of 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase EC#: 3.1.4.56
Synonyms MJ0837 gene product, MptB
EC Number 3.1.4.56
CAS Registry Number
Comments Hydrolyzes 7,8-dihydroneopterin 2′,3′-cyclic phosphate, a step in tetrahydromethanopterin biosynthesis. In vitro the enzyme forms 7,8-dihydroneopterin 2′-phosphate and 7,8- dihydroneopterin 3′-phosphate at a ratio of 4:1.
Cofactor Fe(2+); Zn(2+).
History
Reactions (1) 7,8-dihydroneopterin 2′,3′-cyclic phosphate + H(2)O = 7,8- dihydroneopterin 3′-phosphate. (2) 7,8-dihydroneopterin 2′,3′-cyclic phosphate + H(2)O = 7,8- dihydroneopterin 2′-phosphate.

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