7alpha-hydroxysteroid dehydrogenase EC#: 1.1.1.159; ChemWhat Code: 1373216
| Product Name | 7alpha-hydroxysteroid dehydrogenase |
| Example Structure |  |
| Synonyms | 7-alpha-HSDH, 7-HSDH, 7alpha-HSD, 7alpha-HSDH, 7alpha-hydroxy steroid dehydrogenase, 7alpha-hydroxysteroid dehydrogenase, Bile acid-inducible protein, CA 7alpha-HSDH, Ca7alpha-HSDH, dehydrogenase, 7alpha-hydroxy steroid |
| EC Number | 1.1.1.159 |
| CAS Registry Number | 39361-64-3 |
| Comments | Catalyses the oxidation of the 7¦Á-hydroxy group of bile acids and alcohols both in their free and conjugated forms. The Bacteroides fragilis and Clostridium enzymes can also utilize NADP+. |
| Cofactor | |
| History | |
| Reactions | 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + NAD(+) = 3-alpha,12-alpha-dihydroxy-7-oxo-5-beta-cholanate + Nadh. |
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