8-oxoguanine deaminase EC#: 3.5.4.32; ChemWhat Code: 1381477
Product Name | 8-oxoguanine deaminase |
Example Structure | |
Synonyms | 8-OGD, Pa0142 |
EC Number | 3.5.4.32 |
CAS Registry Number | |
Comments | Zn2+?is bound to the active site. 8-Oxoguanine is formed via the oxidation of guanine within DNA by reactive oxygen species. If uncorrected, this modification leads to the incorporation of 8-oxoG:A mismatches and eventually to G:C to T:A transversions. |
Cofactor | Zn2+ |
History | |
Reactions | 8-oxoguanine + H(2)O = urate + NH(3). |
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