Recombinant Exendin-4 (rExendin-4, P26349, ) CAS#: 651-01-1816

Official Full Name Recombinant Exendin-4 (rExendin-4)
Squence Squence of Recombinant Exendin-4
Amino Acid Sequence HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS
Synonyms Exenatide
Accession Number P26349
GeneID
Summary
Source Escherichia coli.
Molecular Weight Approximately 4.2 kDa, a single non-glycosylated polypeptide chain containing 39 amino acids.
Biological Activity 1. Regulates Glucose levels rapidly;2. Reduces Insulin resistance;3. Reduces Glucagon;4. Reduces HbA1c;5. Stimulates beta cell growth which stimulates insulin production.
Appearance Sterile filtered white lyophilized (freeze-dried) powder.
Formulation Lyophilized from a 0.2 um filtered solution in PBS, pH 7.4.
Endotoxin Less than 10 EU/mg of rExendin-4 as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
References
SDS-PAGE SDS-PAGE of Recombinant Exendin-4
Safety Data Sheet (SDS) Download Click to download
Technical Data Sheet (TDS) Download Click to download

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