| Official Full Name |
Recombinant Exendin-4 (rExendin-4) |
| Squence |
 |
| Amino Acid Sequence |
HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS |
| Synonyms |
Exenatide |
| Accession Number |
P26349 |
| GeneID |
|
| Summary |
|
| Source |
Escherichia coli. |
| Molecular Weight |
Approximately 4.2 kDa, a single non-glycosylated polypeptide chain containing 39 amino acids. |
| Biological Activity |
1. Regulates Glucose levels rapidly;2. Reduces Insulin resistance;3. Reduces Glucagon;4. Reduces HbA1c;5. Stimulates beta cell growth which stimulates insulin production. |
| Appearance |
Sterile filtered white lyophilized (freeze-dried) powder. |
| Formulation |
Lyophilized from a 0.2 um filtered solution in PBS, pH 7.4. |
| Endotoxin |
Less than 10 EU/mg of rExendin-4 as determined by LAL method. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| References |
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| SDS-PAGE |
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| Safety Data Sheet (SDS) Download |
Click to download |
| Technical Data Sheet (TDS) Download |
Click to download |
