| Official Full Name |
Recombinant Human B cell Activating Factor Rececptor/TNFRSF13C (rHuBAFFReceptor/TNFRSF13C) |
| Squence |
 |
| Amino Acid Sequence |
MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG |
| Synonyms |
BAFFR, TNFRSF13C |
| Accession Number |
Q96RJ3 |
| GeneID |
115650 |
| Summary |
|
| Source |
Escherichia coli. |
| Molecular Weight |
Approximately 7.8 kDa, a single non-glycosylated polypeptide chain containing 76 amino acids. |
| Biological Activity |
Fully biologically active when compared to standard. The ED50 as determined by its ability to block BAFF induced mouse splenocyte survival is 1.0-5.0 ug/ml in the presence of 1.0 ug/ml of rHuBAFF. |
| Appearance |
Sterile filtered white lyophilized (freeze-dried) powder. |
| Formulation |
Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 8.0, 500 mM NaCl. |
| Endotoxin |
Less than 1 EU/ug of rHuBAFF-R as determined by LAL method. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| References |
1. Castigli E, Wilson SA, Scott S, et al. 2005. J Exp Med, 201: 35-9.2. Nakajima K, Itoh K, Nagatani K, et al. 2007. Scand J Rheumatol, 36: 365-72.3. Zhu XJ, Shi Y, Peng J, et al. 2009. Blood, 114: 5362-7.4. Thibault-Espitia A, Foucher Y, Danger R, et al. 2012. Am J Transplant, 12: 2754-62. |
| SDS-PAGE |
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| Safety Data Sheet (SDS) Download |
Click to download |
| Technical Data Sheet (TDS) Download |
Click to download |
