| Official Full Name |
Recombinant Human Cyclin-Dependent Kinase Inhibitor 2A, Isoform 1 (rHup16-INK4a) |
| Squence |
 |
| Amino Acid Sequence |
MEPAAGSSME PSADWLATAA ARGRVEEVRA LLEAGALPNA PNSYGRRPIQ VMMMGSARVA ELLLLHGAEP NCADPATLTR PVHDAAREGF LDTLVVLHRA GARLDVRDAW GRLPVDLAEE LGHRDVARYL RAAAGGTRGS NHARIDAAEG PSDIPD |
| Synonyms |
CDK4I, MTS-1, p16INK4A |
| Accession Number |
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| GeneID |
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| Summary |
|
| Source |
Escherichia coli. |
| Molecular Weight |
Approximately 16.5 kDa, a single non-glycosylated polypeptide chain containing 156 amino acids. |
| Biological Activity |
No data available. |
| Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation |
Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4. |
| Endotoxin |
Less than 1 EU/ug of rHuP16-INK4a as determined by LAL method. |
| Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| References |
1. Buda G, Maggini V, Galimberti S, et al. 2007. Leuk Res, 31: 569-70.2. Komiya A, Suzuki H, Aida S, et al. 1995. Jpn J Cancer Res, 86: 622-5.3. Jares P, Fernandez PL, Nadal A, et al. 1997. Oncogene, 15: 1445-53.4. Mori T, Miura K, Aoki T, et al. 1994. Cancer Res, 54: 3396-7. |
| SDS-PAGE |
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| Safety Data Sheet (SDS) Download |
Click to download |
| Technical Data Sheet (TDS) Download |
Click to download |
