Recombinant Human soluble Receptor Activator of Nuclear Factor kappa-B Receptor/TNFRSF11A (rHusRANKReceptor/TNFRSF11A, Q9Y6Q6, 8792) CAS#: 103-1818-1816; ChemWhat Code: 1405233

Official Full Name Recombinant Human soluble Receptor Activator of Nuclear Factor kappa-B Receptor/TNFRSF11A (rHusRANKReceptor/TNFRSF11A)
Squence Squence of Recombinant Human soluble Receptor Activator of Nuclear Factor kappa-B Receptor/TNFRSF11A
Amino Acid Sequence QIAPPCTSEK HYEHLGRCCN KCEPGKYMSS KCTTTSDSVC LPCGPDEYLD SWNEEDKCLL HKVCDTGKAL VAVVAGNSTT PRRCACTAGY HWSQDCECCR RNTECAPGLG AQHPLQLNKD TVCKPCLAGY FSDAFSSTDK CRPWTNCTFL GKRVEHHGTE KSDAVCSSSL PARK
Synonyms
Accession Number Q9Y6Q6
GeneID 8792
Summary
Source
Molecular Weight Approximately 19.1 kDa, a single non-glycosylated polypeptide chain containing 174 amino acids.
Biological Activity Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit sRANK Ligand induced nuclear factor kappa B(NFkappaB) in RAW 264.7 cells is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg in the presence of 15 ng/ml of recombinant sRANK Ligand.
Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation Lyophilized from a 0.2 um filtered concentrated solution in 20 mM Tris-HCl, pH 8.0, 150mM NaCl.
Endotoxin Less than 0.1 EU/ug of rHusRANK Receptor as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
References
SDS-PAGE SDS-PAGE of Recombinant Human soluble Receptor Activator of Nuclear Factor kappa-B Receptor/TNFRSF11A
Safety Data Sheet (SDS) Download Click to download
Technical Data Sheet (TDS) Download Click to download

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