Recombinant Murine Thrombopoietin (rMuTPO, P40226, 21832) CAS#: 122-06-1816; ChemWhat Code: 1405154

Official Full NameRecombinant Murine Thrombopoietin (rMuTPO)
SquenceSquence of Recombinant Murine Thrombopoietin
Amino Acid SequenceSPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF
Synonyms
Accession NumberP40226
GeneID21832
Summary
Source
Molecular WeightApproximately 18.7 kDa, a single non-glycosylated polypeptide chain containing 174 amino acids.
Biological ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human MO7e cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 × 106 IU/mg.
AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
FormulationLyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4, with 5% Trehalose.
EndotoxinLess than 0.1 EU/ug of rMuTPO as determined by LAL method.
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
References
SDS-PAGESDS-PAGE of Recombinant Murine Thrombopoietin
Safety Data Sheet (SDS) DownloadClick to download
Technical Data Sheet (TDS) DownloadClick to download

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