Recombinant Murine soluble Tumor Necrosis Factor Receptor Type II/TNFRSF1B (rMusTNFRII/TNFRSF1B, P25119, 21938) CAS#: 123-2918-1816

Official Full Name Recombinant Murine soluble Tumor Necrosis Factor Receptor Type II/TNFRSF1B (rMusTNFRII/TNFRSF1B)
Squence Squence of Recombinant Murine soluble Tumor Necrosis Factor Receptor Type II/TNFRSF1B
Amino Acid Sequence VPAQVVLTPY KPEPGYECQI SQEYYDRKAQ MCCAKCPPGQ YVKHFCNKTS DTVCADCEAS MYTQVWNQFR TCLSCSSSCT TDQVEIRACT KQQNRVCACE AGRYCALKTH SGSCRQCMRL SKCGPGFGVA SSRAPNGNVL CKACAPGTFS DTTSSTDVCR PHRICSILAI PGNASTDAVC APESPTLSAI PRTLYVSQPE PTRSQPLDQE PGPSQTPSIL TSLGSTPIIE QSTKGG
Synonyms
Accession Number P25119
GeneID 21938
Summary
Source
Molecular Weight Approximately 25.3 kDa, a single non-glycosylated polypeptide chain containing 236 amino acids.
Biological Activity Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 2 ug/ml, corresponding to a specific activity of > 500 IU/mg in the presence of 0.1 ng/mL of rMuTNF-alpha.
Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation Lyophilized from a 0.2 um filtered solution in PBS, pH 7.4.
Endotoxin Less than 0.1 EU/ug of rMusTNF RII/TNFRSF1B as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
References
SDS-PAGE SDS-PAGE of Recombinant Murine soluble Tumor Necrosis Factor Receptor Type II/TNFRSF1B
Safety Data Sheet (SDS) Download Click to download
Technical Data Sheet (TDS) Download Click to download

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