Official Full Name |
Recombinant Rat Interleukin-2, Liquid (rRtIL-2,Liquid) |
Squence |
 |
Amino Acid Sequence |
APTSSPAKET QQHLEQLLLD LQVLLRGIDN YKNLKLPMML TFKFYLPKQA TELKHLQCLE NELGALQRVL DLTQSKSFHL EDAGNFISNI RVTVVKLKGS ENKFECQFDD EPATVVEFLR RWIAICQSII STMTQ |
Synonyms |
T-cell Growth Factor, CGF |
Accession Number |
P17108 |
GeneID |
116562 |
Summary |
|
Source |
Escherichia coli. |
Molecular Weight |
Approximately 15.5 kDa, a single non-glycosylated polypeptide chain containing 135 amino acids. |
Biological Activity |
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.2 ng/ml, corresponding to a specific activity of > 5.0 × 106 IU/mg. |
Appearance |
Sterile Colorless liquid. |
Formulation |
A 0.2 um filtered concentrated sterile solution in 10 mM sodium citrate, pH 4.0, 30 % glycerol. |
Endotoxin |
Less than 1 EU/ug of rRtIL-2, Liquid as determined by LAL method. |
Reconstitution |
|
Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 6 months from date of receipt, -20 to -70 °C as supplied.- 3 months, -20 to -70 °C under sterile conditions after opening. |
References |
1. Ma, A., R. Koka, and P. Burkett. 2006. Annu Rev Immunol, 24: 657-79.2. Taniguchi, T., H. Matsui, T. Fujita, et al. 1983. Nature, 302: 305-10.3. Liparoto, S.F., D.G. Myszka, Z. Wu, et al. 2002. Biochemistry, 41: 2543-51.4. Bodnar, A., E. Nizsaloczki, G. Mocsar, et al. 2008. Immunol Lett, 116: 117-25.5. Mosmann, T.R., T. Yokota, R. Kastelein, et al. 1987. J Immunol, 138: 1813-6. |
SDS-PAGE |
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Safety Data Sheet (SDS) Download |
Click to download |
Technical Data Sheet (TDS) Download |
Click to download |