acetate kinase EC#: 2.7.2.1; ChemWhat Code: 1378635
| Product Name | acetate kinase |
| Example Structure | ![]() |
| Synonyms | acetate kinase (phosphorylating), acetic kinase, acetokinase, ACK, ackA, AckA1, AckA2, ACKase, AK, ATP-ecoAK, ATP-specific AK, EAK, MM_0495, Sak, StAckA, urkinase |
| EC Number | 2.7.2.1 |
| CAS Registry Number | 9027-42-3 |
| Comments | Requires Mg2+?for activity. While purified enzyme from?Escherichia coli?is specific for acetate [4], others have found that the enzyme can also use propanoate as a substrate, but more slowly [7]. Acetate can be converted into the key metabolic intermediate acetyl-CoA by coupling acetate kinase with EC?2.3.1.8, phosphate acetyltransferase. Both this enzyme and EC?2.7.2.15, propionate kinase, play important roles in the production of propanoate [9]. |
| Cofactor | Mg2+ |
| History | |
| Reactions | Atp + acetate = adp + acetyl phosphate. |
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