acetoacetyl-CoA synthase EC#: 2.3.1.194; ChemWhat Code: 1377005
| Product Name | acetoacetyl-CoA synthase |
| Example Structure |  |
| Synonyms | AACS, Acetoacetyl-CoA synthase, Acetoacetyl-CoA synthetase, acetoacetyl-coenzyme A synthase, acetoacetyl-coenzyme A synthesizing enzyme, More, NphT7, nphT7SCL, thiolase superfamily acetoacetyl-CoA synthase |
| EC Number | 2.3.1.194 |
| CAS Registry Number | |
| Comments | The enzyme from the soil bacterium Streptomyces sp. CL190 produces acetoacetyl-CoA to be used for mevalonate production via the mevalonate pathway. Unlike the homologous EC 2.3.1.180 (¦Â-ketoacyl-[acyl-carrier-protein] synthase III), this enzyme does not accept malonyl-[acyl-carrier-protein] as a substrate. |
| Cofactor | |
| History | |
| Reactions | Acetyl-CoA + malonyl-CoA = acetoacetyl-CoA + CoA + CO(2). |
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