acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase EC#: 2.4.1.147; ChemWhat Code: 1377437
| Product Name | acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase |
| Example Structure |  |
| Synonyms | acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-mucin beta(1-3)-, beta3-N-acetylglucosaminyltransferase-6, beta3Gn-T6, beta3GnT-6, C3 beta3GnT6, C3GnT, core 3 beta 1,3-N-acetylglucosaminyltransferase, core 3 beta1,3-N-acetylglucosaminyltransferase, core 3 beta3-GlcNAc-T, core 3 beta3-N-acetylglucosaminyltransferase 6, core 3 synthase, core 3beta-GlcNAc-transferase, core3 O-glycan synthase, core3 synthase, mucin core 3 beta3-GlcNAc-transferase, O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III, uridine diphosphoacetylglucosamine-mucin beta(1-3)-acetylglucosaminyltransferase |
| EC Number | 2.4.1.147 |
| CAS Registry Number | 87927-96-6 |
| Comments | The product of the enzyme is known as core 3, one of the eight core structures of mucin-type O-glycans. O-Linked glycans are polysaccharides or oligosaccharides that are linked to a protein via the oxygen atom in the side chain of an L-serine or L-threonine residue. |
| Cofactor | |
| History | |
| Reactions | UDP-N-acetyl-alpha-D-glucosamine + O(3)-(N-acetyl-alpha-D- galactosaminyl)-L-threonyl/L-seryl-[protein] = Udp + O(3)-(N-acetyl-beta- D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl)-L- threonyl/L-seryl-[protein]. |
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