acireductone dioxygenase (Ni2+-requiring) EC#: 1.13.11.53; ChemWhat Code: 1374978
Product Name | acireductone dioxygenase (Ni2+-requiring) |
Example Structure | |
Synonyms | 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase, aci-reductone dioxygenase, acidoreductone dioxygenase, acireductone dioxygenase, ADI1, ARD, ARD1, human aci-reductone dioxygenase 1, membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1, MtnD, Ni(II)-ARD |
EC Number | 1.13.11.53 |
CAS Registry Number | |
Comments | Requires Ni2+. If iron(II) is bound instead of Ni2+, the reaction catalysed by EC 1.13.11.54, acireductone dioxygenase [iron(II)-requiring], occurs instead [1]. The enzyme from Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway. |
Cofactor | Ni2+ |
History | |
Reactions | 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 3-(methylthio)propanoate + formate + Co. |
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