Acrocylindropepsin EC#: 3.4.23.28; ChemWhat Code: 1380892

Product Name Acrocylindropepsin
Example Structure Example Structure of Acrocylindropepsin EC#: 3.4.23.28
Synonyms Acrocylindricum proteinase, Acrocylindrium acid proteinase, Acrocylindrium proteinase, EC 3.4.23.6, EC 3.4.99.1, More, Proteinase, Acrocylindricum
EC Number 3.4.23.28
CAS Registry Number 37288-84-9
Comments From the imperfect fungus?Acrocylindrium?sp. Has a very low pH optimum on casein of 2.0. In peptidase family?A1?(pepsin A family). Formerly EC?3.4.99.1?and included in EC?3.4.23.6.
Cofactor
History
Reactions Preference for hydrophobic residue at P1 and P1′. Action on the B chain of insulin is generally similar to that of pepsin A, but it also cleaves 6-Leu-|-Cys(SO(3)H)-7, 21-Glu-|-Arg-22 and 3-Asn-|-Gln-4, although not 4-Gln-|-His-5.

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