acrylyl-CoA reductase (NADPH) EC#: 1.3.1.84; ChemWhat Code: 1374049
| Product Name | acrylyl-CoA reductase (NADPH) |
| Example Structure |  |
| Synonyms | Acr, acryloyl-CoA reductase, acryloyl-CoA reductase (NADPH), acryloyl-coenzyme A reductase, acrylyl-CoA reductase, acrylyl-coenzyme A reductase, AcuI, Msed_1426, NADPH-dependent acryloyl-CoA reductase activity, NADPH-dependent acrylyl-CoA reductase, RSP_1434, SPO1914, SPO_1914, yhdH |
| EC Number | 1.3.1.84 |
| CAS Registry Number | |
| Comments | Catalyses a step in the 3-hydroxypropionate/4-hydroxybutyrate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea [1]. The reaction is catalysed in the opposite direction to that shown. The enzyme from Sulfolobus tokodaii does not act on either NADH or crotonyl-CoA [2]. Different from EC 1.3.1.8, which acts only on enoyl-CoA derivatives of carbon chain length 4 to 16. Contains Zn2+. |
| Cofactor | Zn2+ |
| History | |
| Reactions | Propanoyl-CoA + NADP(+) = acrylyl-CoA + Nadph. |
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