[acyl-carrier-protein] phosphodiesterase EC#: 3.1.4.14; ChemWhat Code: 1379580

Product Name [acyl-carrier-protein] phosphodiesterase
Example Structure Example Structure of [acyl-carrier-protein] phosphodiesterase EC#: 3.1.4.14
Synonyms 4′-phosphopantetheine hydrolase, ACP hydrolase, ACP hydrolyase, ACP phosphodiesterase, AcpH, acyl carrier protein phosphodiesterase, holofatty acid synthetase hydrolase
EC Number 3.1.4.14
CAS Registry Number 37288-21-4
Comments The enzyme cleaves acyl-[acyl-carrier-protein] species with acyl chains of 6-16 carbon atoms although it appears to demonstrate a preference for the unacylated acyl-carrier-protein (ACP) and short-chain ACPs over the medium- and long-chain species [3]. Deletion of the gene encoding this enzyme abolishes ACP prosthetic-group turnover in vivo [3]. Activation of apo-ACP to form the holoenzyme is carried out by EC?2.7.8.7, holo-[acyl-carrier-protein] synthase.
Cofactor
History
Reactions Holo-[acyl-carrier-protein] + H(2)O = 4′-phosphopantetheine + apo-[acyl- carrier-protein].

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