acyl-CoA (9+3)-desaturase EC#: 1.14.19.6; ChemWhat Code: 1375767

Product Name acyl-CoA (9+3)-desaturase
Example Structure Example Structure of acyl-CoA (9+3)-desaturase EC#: 1.14.19.6
Synonyms acyl-CoA (9+3)-desaturase, acyl-lipid DELTA12-desaturase, Cofad2-2, CSFAD2A, D12Des, DELTA 12 desaturase, delta 12 fatty acid desaturases, delta-12 fatty acid desaturase, delta-12 fatty acid desaturase 2, DELTA12 acyl-lipid desaturase, DELTA12 desaturase, DELTA12 FAD, DELTA12 fatty acid desaturase, DELTA12 oleate hydroxylase, DELTA12(omega6)-desaturase, DELTA12-acyl-lipid desaturase, DELTA12-desaturase, DELTA12-desaturase system, DELTA12-FAD, DELTA12-fatty acid desaturase, DELTA12-fatty acyl-CoA desaturase, DELTA12des, DELTA12DS, Des12, DesA, egFAD2, FAD-2, FAD2, FAD2-2, FAD2A, FADS1, FADS2, FAH, FAT-2, fatty acid desaturase-2, Fm2, KlFAD2, Le-FAD2, LKFAD15, microsomal Delta-12 fatty acid desaturase, microsomal delta-12 oleate desaturase, microsomal oleate desaturase, microsomal omega-6 fatty acid desaturase, oleoyl coenzyme A desaturase, oleoyl-CoA DELTA12 desaturase, oleoyl-DELTA12 desaturase, oleoyl-DELTA12/linoleoyl-DELTA3 desaturase, omega-6 fatty acid desaturase, PtFAD2, PtFAD6, seed-specific delta-12 fatty acid desaturase 2
EC Number 1.14.19.6
CAS Registry Number
Comments This microsomal enzyme introduces a cis double bond at position 12 of fatty-acyl-CoAs that contain a cis double bond at position 9. When acting on 19:1¦¤10 fatty acyl-CoA the enzyme from the pathogenic protozoan Trypanosoma brucei introduces the new double bond at position 13, indicating that the new double bond is introduced three carbons from the existing cis double bond, towards the methyl-end of the fatty acid. Requires cytochrome b5 as the electron donor [4].
Cofactor
History
Reactions (1) Oleoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = linoleoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O. (2) Palmitoleoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = (9Z,12Z)- hexadeca-9,12-dienoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O.

Buy Reagent

No reagent supplier? Send quick inquiry to ChemWhat
Want to be listed here as a reagent supplier? (Paid service) Click here to contact ChemWhat

Approved Manufacturers

Want to be listed as an approved manufacturer (Requires approvement)? Please download and fill out this form and send back to approved-manufacturers@chemwhat.com

Contact Us for Other Help

Contact us for other information or services Click here to contact ChemWhat