acyl-CoA dehydrogenase (NADP+) EC#: 1.3.1.8; ChemWhat Code: 1373947
| Product Name | acyl-CoA dehydrogenase (NADP+) |
| Example Structure |  |
| Synonyms | 2-enoyl-CoA reductase, 2-trans enoyl-CoA reductase, 2-trans-enoyl-CoA reductase, acyl coenzyme A dehydrogenase (nicotinamide adenine dinucleotide phosphate), CCR, crotonyl CoA reductase, crotonyl coenzyme A reductase, crotonyl-CoA reductase, crotonyl-coenzyme A reductase, dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate), enoyl coenzyme A reductase, enoyl-CoA reductase, MCAD, medium-chain acyl-CoA dehydrogenase, NADPH:enoyl-CoA oxidoreductase, NbECR, RCCR, trans-2-enoyl-CoA reductase |
| EC Number | 1.3.1.8 |
| CAS Registry Number | 37251-07-3 |
| Comments | The liver enzyme acts on enoyl-CoA derivatives of carbon chain length 4 to 16, with optimum activity on 2-hexenoyl-CoA. In Escherichia coli, cis-specific and trans-specific enzymes exist [EC 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH) and EC 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)]. |
| Cofactor | |
| History | |
| Reactions | Acyl-CoA + NADP(+) = 2,3-dehydroacyl-CoA + Nadph. |
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