ADAM10 endopeptidase EC#: 3.4.24.81; ChemWhat Code: 1381089
| Product Name | ADAM10 endopeptidase |
| Example Structure |  |
| Synonyms | a disintegrin and metalloprotease 10, a disintegrin and metalloproteinase 10, ADAM 10, ADAM-10, ADAM10, CD23 metalloprotease, kuzbanian, Kuzbanian protein, mammalian disintegrin-metalloprotease, metalloproteinase 10, metalloproteinase ADAM10, metalloproteinase Kuzbanian, metalloproteinase MADM, metalloproteinase-disintegrin, myelin-associated disintegrin metalloproteinase, notch proteinase, transmembrane metzinkin-protease of the a disintegrin and metalloproteinase family-10 |
| EC Number | 3.4.24.81 |
| CAS Registry Number | |
| Comments | In peptidase family?M12. Partially responsible for the “¦Á-secretase” activity in brain that degrades the potentially harmful ¦Â-amyloid peptide. Work with ADAM10-deficient mice supports a role in Notch signalling. |
| Cofactor | Zn2+ |
| History | |
| Reactions | Endopeptidase of broad specificity. |
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