ADAMTS-4 endopeptidase EC#: 3.4.24.82; ChemWhat Code: 1381091

Product Name ADAMTS-4 endopeptidase
Example Structure Example Structure of ADAMTS-4 endopeptidase EC#: 3.4.24.82
Synonyms a disintegrin and metalloprotease with thrombospondin motifs-4, a disintegrin and metalloproteinase with thrombospondin motif, a disintegrin and metalloproteinase with thrombospondin motifs-4, a disintegrin and metalloproteinase with thrombospondin-1-like motifs, ADAMTS 4, ADAMTS-1, ADAMTS-4, ADAMTS-4 [a disintegrin and metalloproteinase with thrombospondin motifs-4], ADAMTS-4-2, ADAMTS4, agg-1, aggrecanase, aggrecanase 1, aggrecanase-1, disintegrin and metalloproteinase with thrombospondin motif 4, TS-4
EC Number 3.4.24.82
CAS Registry Number
Comments In peptidase family?M12. Thought to be biologically significant for the degradation of the aggrecan component of cartilage matrix.
Cofactor Zn2+
History
Reactions Glutamyl endopeptidase; bonds cleaved include 370-Thr-Glu-Gly-Glu-|-Ala- Arg-Gly-Ser-377 in the interglobular domain of mammalian aggrecan.

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