adenain EC#: 3.4.22.39; ChemWhat Code: 1380750
| Product Name | adenain |
| Example Structure |  |
| Synonyms | Ad L3 23K proteinase, adenain 5, adenain 8, adenoviral protease, adenovirus endopeptidase, adenovirus proteinase, adenovirus type 2 protease, AVP, AVP5, AVP8, cysteine endopeptidase, cysteine endoprotease, cysteine peptidase, cysteine protease, cysteine proteinase, endoprotease, L-cysteine proteinase, L3, L3/p23, Late L3 23 kDa protein, mercapto proteinase, oryzain, p23, papain-like cysteine protease, sulfhydryl esterase, sulfhydryl protease, sulfhydryl proteinase, thiol endopeptidase, thiol endoproteinase, thiol protease, thiol proteinase, thioprotease, trigger peptidase |
| EC Number | 3.4.22.39 |
| CAS Registry Number | 369652-03-9 |
| Comments | A cysteine endopeptidase from adenoviruses, the type example of peptidase family C5, with a protein fold unlike that known for any other peptidase [2]. Activity is greatly stimulated by the binding to the enzyme of an 11-residue peptide from the adenovirus capsid protein pre-VI at a site separate from the active site [1]. |
| Cofactor | |
| History | |
| Reactions | Cleaves proteins of the adenovirus and its host cell at two consensus sites: -Yaa-Xaa-Gly-Gly-|-Xaa- and -Yaa-Xaa-Gly-Xaa-|-Gly- (in which Yaa is Met, Ile or Leu, and Xaa is any amino acid). |
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