adenylyl-sulfate reductase (glutathione) EC#: 1.8.4.9; ChemWhat Code: 1374726

Product Name adenylyl-sulfate reductase (glutathione)
Example Structure Example Structure of adenylyl-sulfate reductase (glutathione) EC#: 1.8.4.9
Synonyms 3′-phosphoadenosine-5′-phosphosulfate reductase homolog 19, 3′-phosphoadenosine-5′-phosphosulfate reductase homolog 26, 3′-phosphoadenosine-5′-phosphosulfate reductase homolog 43, 5′-adenylylsulfate reductase, 5-adenosinephosphosulphate reductase, adenosine 5′-phosphosulfate reductase, adenosine 5-phosphosulfate reductase, adenosine-5′-phosphosulfate reductase, APR, APR1p, APR2, APS reductase, At1g62180, CysH, EC 1.8.99.2, EiAPR, More, PAPS reductase homolog 19, PAPS reductase homolog 26, PAPS reductase homolog 43, plant-type 5′-adenylylsulfate reductase, PpAPR-B, Prh-19, Prh-26, Prh-43
EC Number 1.8.4.9
CAS Registry Number
Comments This enzyme differs from EC 1.8.99.2, adenylyl-sulfate reductase (acceptor), in using glutathione as the reductant. Glutathione can be replaced by ¦Ã-glutamylcysteine or dithiothreitol, but not by thioredoxin, glutaredoxin or mercaptoethanol. The enzyme from the mouseear cress, Arabidopsis thaliana, contains a glutaredoxin-like domain. The enzyme is also found in other photosynthetic eukaryotes, e.g., the Madagascar periwinkle, Catharanthus roseus and the hollow green seaweed, Enteromorpha intestinalis.
Cofactor
History
Reactions Amp + sulfite + glutathione disulfide = adenylyl sulfate + 2 glutathione.

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