aklaviketone reductase EC#: 1.1.1.362; ChemWhat Code: 1373484

Product Name aklaviketone reductase
Example Structure Example Structure of aklaviketone reductase EC#: 1.1.1.362
Synonyms
EC Number 1.1.1.362
CAS Registry Number
Comments The enzyme is involved in the synthesis of the aklavinone aglycone, a common precursor for several anthracycline antibiotics including aclacinomycins, daunorubicin and doxorubicin. The enzyme from the Gram-negative bacterium Streptomyces sp. C5 produces daunomycin.
Cofactor
History
Reactions Aklavinone + NADP(+) = aklaviketone + Nadph.

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