aklavinone 12-hydroxylase EC#: 1.14.13.180; ChemWhat Code: 1375415

Product Name aklavinone 12-hydroxylase
Example Structure Example Structure of aklavinone 12-hydroxylase EC#: 1.14.13.180
Synonyms DnrF, RdmE
EC Number 1.14.13.180
CAS Registry Number
Comments The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins. The enzyme from Streptomyces purpurascens is an FAD monooxygenase.
Cofactor FAD
History
Reactions Aklavinone + Nadph + O(2) = epsilon-rhodomycinone + NADP(+) + H(2)O.

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