alcohol-forming fatty acyl-CoA reductase EC#: 1.2.1.84; ChemWhat Code: 1373845
| Product Name | alcohol-forming fatty acyl-CoA reductase |
| Example Structure |  |
| Synonyms | alcohol-forming fatty acyl-CoA reductase, CER4, CG1443, FAR, FAR1, FAR2, FAR3, FAR4, FAR5, fatty acyl-CoA reductase, fatty acyl-CoA reductase 1, fatty acyl-CoA reductase 3, fatty acyl-CoA:NADPH oxidoreductase (long chain alcohol forming), fatty acyl-Coenzyme A reductase, intestinal acyl-CoA reductase, male sterility C-terminal domain, male sterility domain-containing protein 1, Maqu_2220, Maqu_2507, peroxisomal fatty acyl-CoA reductase 1, PsFAR I, PsFAR II, wat, Waterproof |
| EC Number | 1.2.1.84 |
| CAS Registry Number | |
| Comments | The enzyme has been characterized from the plant Simmondsia chinensis (jojoba). The alcohol is formed by a four-electron reduction of fatty acyl-CoA. Although the reaction proceeds through an aldehyde intermediate, a free aldehyde is not released. The recombinant enzyme was shown to accept saturated and mono-unsaturated fatty acyl-CoAs of 16 to 22 carbons. |
| Cofactor | |
| History | |
| Reactions | A long-chain acyl-CoA + 2 nadph = CoA + a long-chain alcohol + 2 NADP(+). |
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