| Product Name |
aliphatic (R)-hydroxynitrile lyase |
| Example Structure |
 |
| Synonyms |
(R)-HNL, (R)-hydroxynitrile lyase, (R)-Oxynitrilase, Acetone cyanohydrin lyase, Hydroxynitrile lyase, LuHNL |
| EC Number |
4.1.2.46 |
| CAS Registry Number |
|
| Comments |
The enzyme contains Zn2+?[1]. The enzyme catalyses the stereoselective synthesis of aliphatic (R)-cyanohydrins [1]. No activity towards mandelonitrile and 4-hydroxymandelonitrile [5]. Natural substrates for the (R)-oxynitrilase from?Linum usitatissimum?are acetone and butan-2-one, which are the building blocks of the cyanogen glycosides in?Linum, linamarin and lotaustralin, or linustatin and neolinustatin, respectively [4]. |
| Cofactor |
Zn2+ |
| History |
|
| Reactions |
(2R)-2-hydroxy-2-methylbutanenitrile = cyanide + butan-2-one. |