alpha-1,2-colitosyltransferase EC#: 2.4.1.341; ChemWhat Code: 1377682
Product Name | alpha-1,2-colitosyltransferase |
Example Structure | |
Synonyms | alpha1,2-ColT, wbgN |
EC Number | 2.4.1.341 |
CAS Registry Number | |
Comments | The enzyme, characterized from the bacterium Escherichia coli O55:H7, participates in the biosynthesis of an O-antigen. The reaction involves anomeric inversion, and does not require any metal ions. The enzyme is highly specific towards the acceptor, exclusively recognizing lacto-N-biose, but can accept GDP-L-fucose as the donor with almost the same activity as with GDP-¦Â-L-colitose. |
Cofactor | |
History | |
Reactions | GDP-beta-L-colitose + beta-D-galactopyranosyl-(1->3)-N-acetyl-D- glucosamine = Gdp + alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N- acetyl-D-glucosamine. |
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