alpha-1,2-colitosyltransferase EC#: 2.4.1.341; ChemWhat Code: 1377682

Product Name alpha-1,2-colitosyltransferase
Example Structure Example Structure of alpha-1,2-colitosyltransferase EC#: 2.4.1.341
Synonyms alpha1,2-ColT, wbgN
EC Number 2.4.1.341
CAS Registry Number
Comments The enzyme, characterized from the bacterium Escherichia coli O55:H7, participates in the biosynthesis of an O-antigen. The reaction involves anomeric inversion, and does not require any metal ions. The enzyme is highly specific towards the acceptor, exclusively recognizing lacto-N-biose, but can accept GDP-L-fucose as the donor with almost the same activity as with GDP-¦Â-L-colitose.
Cofactor
History
Reactions GDP-beta-L-colitose + beta-D-galactopyranosyl-(1->3)-N-acetyl-D- glucosamine = Gdp + alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N- acetyl-D-glucosamine.

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