alpha-guaiene synthase EC#: 4.2.3.87; ChemWhat Code: 1382668

Product Name alpha-guaiene synthase
Example Structure Example Structure of alpha-guaiene synthase EC#: 4.2.3.87
Synonyms Pat177, patchoulol synthase, PTS, TPS, TPS24, VIT_19s0014g02590, VvGuaS, VvTPS24
EC Number 4.2.3.87
CAS Registry Number
Comments Requires Mg2+. The enzyme from?Pogostemon cablin?gives 13% ¦Á-guaiene as well as 37% (-)-patchoulol (see EC?4.2.3.70), 13% ¦Ä-guaiene (see EC?4.2.3.93), and traces of at least ten other sesquiterpenoids [1]. In?Aquilaria crassna?three clones of the enzyme gave about 80% ¦Ä-guaiene and 20% ¦Á-guaiene, with traces of ¦Á-humulene. A fourth clone gave 54% ¦Ä-guaiene and 45% ¦Á-guaiene [2].
Cofactor Mg2+
History
Reactions (2E,6E)-farnesyl diphosphate = alpha-guaiene + diphosphate.

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