alpha1, 3-fucosyltransferase; alpha1, 3FucT CAS#: 37277-69-3 EC#: 2.4.1.65; ChemWhat Code: 1377334

IdentificationPhysical DataSpectra
Route of Synthesis (ROS)Safety and HazardsOther Data

Identification

Product Namealpha1, 3-fucosyltransferase; alpha1, 3FucTrase EC#: 5.1.3.2
IUPAC NameNo data available
Molecular StructureNo data available
CAS Registry Number 37277-69-3
EC Number2.4.1.65
CommentsThis enzyme is the product of the Lewis blood group gene. Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. Although it is a 4-fucosyltransferase, it has a persistent 3-fucosyltransferase activity towards the glucose residue in free lactose. This enzyme fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3, unlike EC 2.4.1.152, 4-galactosyl-N-acetylglucosaminide 3-¦Á-L-fucosyltransferase, which fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4. Enzymes catalysing the 4-¦Á-fucosylation of the GlcNAc in ¦Â-D-Gal-(1¡ú3)-¦Â-GlcNAc sequences (with some activity also as 3-¦Á-fucosyltransferases) are present in plants, where the function in vivo is the modification of N-glycans. In addition, the fucTa gene of Helicobacter strain UA948 encodes a fucosyltransferase with both 3-¦Á- and 4-¦Á-fucosyltransferase activities.
CofactorNo data available
HistoryNo data available
ReactionsGDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R = Gdp + beta-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->4))-N-acetyl-beta-D- glucosaminyl-R.
More informationE. coli recombinant α1,3fucosyltransferase from Helicobacter pylori
alpha1, 3-fucosyltransferase; alpha1, 3FucT CAS 37277-69-3 EC# 2.4.1.65
EINECS NumberNo data available
MDL NumberNo data available
Beilstein Registry NumberNo data available
Synonyms(Lea)-dependent alpha-3/4-fucosyltransferase, alpha 1,3-fucosyltransferase VII, alpha 1,3/4 fucosyltransferase, alpha(1,3) fucosyltransferase, alpha(1,3/1,4) fucosyltransferase III, alpha(1,3/4) fucosyltransferase, alpha(1,3/4)-FUT, alpha-(1,3/1,4)-fucosyltransferase, alpha-(1,3/1,4)-FucT, alpha-(1-3/4)-fucosyltransferase, alpha-(1->4)-L-fucosyltransferase, alpha-1,3 fucosyltransferase, alpha-1,3-fucosyltransferase, alpha-1,3/4-fucosyltransferase, alpha-1,3fucosyltransferase, alpha-1,4 fucosyltransferase, alpha-3-FUT, alpha-3/4 fucosyltransferase, alpha-3/4 fucosyltransferase III, alpha-3/4-FUT, alpha-4-fucosyltransferase, alpha-4-L-fucosyltransferase, alpha1,3 fucosyltransferase, alpha1,3 fucosyltransferase VII, alpha1,3-fucosyltransferase, alpha1,3-fucosyltransferase IX, alpha1,3-fucosyltransferase VI, alpha1,3/1,4FucT III, alpha1,3/4-fucosyltransferase, alpha1,3/4-fucosyltransferase VI, alpha1,3/4-fucosyltransferases-V and -VI, alpha1,3/4-FUT, alpha1,3FucT IV, alpha1,3FucT IX, alpha1,3FucT V, alpha1,3FucT VI, alpha1,3FucT VII, alpha3/4 fucosyltransferase 3, alpha3/4 fucosyltransferases, alpha3/4FucT, alpha4-fucosyltransferase, alpha4-FucT, alphaFucT, beta-acetylglucosaminylsaccharide fucosyltransferase, blood group Lewis alpha-4-fucosyltransferase, blood-group substance Lea-dependent fucosyltransferase, FT-IV, FT-VII, FT3, FT6, FT7, Fuc-T, Fuc-TIII, fucosyltransferase, fucosyltransferase 3, fucosyltransferase 5, fucosyltransferase 6, fucosyltransferase 7, fucosyltransferase IV, fucosyltransferase V, fucosyltransferase VI, fucosyltransferase VII, fucosyltransferase, guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-, fucosyltransferase, guanosine diphosphofucose-glycoprotein 4-alpha-, FucT, FucT III, FucT IV, FucT IX, FucT V, FucT VI, FucT VII, FucT-II, FucT-III, FucT-V, FucT-VI, FucT-VII, FucTIII, FUT III, FUT10, FUT11, FUT3, FUT4, FUT5, FUT6, FUT7, Fut9, GDP-Fuc: beta-D-Galp-(1-3/4)-beta-D-GlcpNAc-(1-4’/3′)-alpha-fucosyltransferase, guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase, Lewis alpha-3-fucosyltransferase, Lewis alpha-3/4-fucosyltransferase, Lewis alpha1-3/4 fucosyltransferase, Lewis blood group alpha1-3/4 fucosyltransferase, Lewis(Le) blood group gene-dependent alpha-3/4-L-fucosyltransferase, SFT3, sFUT5, sperm fucosyltransferase-5, UA948FucT; CAS NO.: 37277-69-3; CAS Number: 37277-69-3
Molecular FormulaNo data available
Molecular WeightNo data available
InChINo data available
InChI KeyNo data available
Canonical SMILESNo data available
Patent Information
No data available

Physical Data

AppearanceNo data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

GHS Hazard StatementsNot Classified
For more detailed information, please visit?ECHA C&L website
Source: European Chemicals Agency (ECHA)
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License URL: https://echa.europa.eu/web/guest/legal-notice
Record Name: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate
URL: https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/213446
Description: The information provided here is aggregated from the “Notified classification and labelling” from ECHA’s C&L Inventory. Read more: https://echa.europa.eu/information-on-chemicals/cl-inventory-database

Other Data

TransportationNot dangerous goods
2-8°C away from light
HS CodeNo data available
Storage2-8°C away from light
Shelf Life1 year
Market PriceUSD
Use Pattern
alpha1, 3-fucosyltransferase; alpha1, 3FucT CAS 37277-69-3 EC 2.4.1.65 is widely used in in vitro diagnostic products and play an important role as key raw materials in biochemical diagnostics, molecular diagnostics, chemiluminescence, biosensors, blood coagulation diagnosis and other products

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