angiotensin-converting enzyme 2 EC#: 3.4.17.23; ChemWhat Code: 1380415
| Product Name | angiotensin-converting enzyme 2 |
| Example Structure |  |
| Synonyms | ACE, ACE 2, ACE-2, ACE-related carboxypeptidase, ACE2, ACE2 homologue, ACEH, Ang converting enzyme 2, angiotensin converting enzyme 2, angiotensin converting enzyme II, angiotensin converting enzyme-2, angiotensin II converting enzyme 2, angiotensin-converting enzyme, angiotensin-converting enzyme 2, angiotensin-converting enzyme homolog, angiotensin-converting enzyme homologue, angiotensin-converting enzyme type 2, angiotensin-converting enzyme-2, angiotensin-converting enzyme-like protein, angiotensin-converting enzyme-related carboxypeptidase, angiotensinase, hACE2, sACE2, soluble angiotensin converting enzyme 2 |
| EC Number | 3.4.17.23 |
| CAS Registry Number | |
| Comments | A transmembrane glycoprotein with an extracellular catalytic domain. Angiotensin-converting enzyme 2 functions as a carboxypeptidase, cleaving a single C-terminal residue from a distinct range of substrates [2]. Catalytic efficiency is 400-fold higher with angiotensin II (1-8) as a substrate than with angiotensin I (1-10). Angiotensin-converting enzyme 2 also efficiently hydrolyzes des-Arg9-bradykinin, but it does not hydrolyze bradykinin [1]. In peptidase family?M2. |
| Cofactor | |
| History | |
| Reactions | Angiotensin Ii + H(2)O = angiotensin-(1-7) + L-phenylalanine. |
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