Anti-T4 (thyroxine T4 CAS#: 51-48-9) Antibody

AntigenDescriptionProperties
Safety InformationImagesOther Info

Antigen

NameThyroxine T4
SynonymsT4; Thyroxine; 51-48-9;

Description

NameAnti-Thyroxine (T4) Antibody
SynonymsAnti-T4 Antibody; Anti-Thyroxine antibody; L-Thyroxine (T4) antibody
HostMouse; Goat; Rabbit
ReactivityAll species
Antibody Product Type  Primary
Conjugate Unconjugated; Biotin; APC; Alkaline Phosphatase (AP); FITC; HRP; PE
SpecifityRecognizes Thyroxine, also known as T4, the major hormone secreted by the follicular cells of the thyroid gland. Its main role is to regulate metabolic processes in the body such as heart rate, along with Triiodothyronine (T3). T4 is involved in thyroid disorders, such as hyperthyroidism and hypothyroidism. 
ApplicationELISA; Immunohistochemistry (IHC); Western Blotting (WB); Immunofluorescence (fixed cells) (IF/ICC); Immunoprecipitation (IP); Cell-ELISA (cELISA); Immunoassay (IA); Immunocytochemistry (ICC)

Properties

FormLiquid/Lyophilized
HandlingThe antibody solution should be gently mixed before use.
Storage ConditionStore at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for a year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ClonalityMonoclonal/Polyclonal
IsotypeIgG

Safety Information

RIDADRNONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable

Images

Thyroxine T4 Antibody in ELISAThyroxine T4 Antibody in ELISA
Thyroxine T4 Antibody in WBThyroxine T4 Antibody in WB

Other Info

About the antigenAntibodies against thyroxine (T4) were detected in a patient of systemic lupus erythematosus associated with chronic thyroiditis and a patient with primary myxedema. Both patients were clincally hypothyroid with elevated serum TSH. Serum T4 values measured with solid phase radioimmunoassay were very high (over 25ug/dl), but were undetected with polyethylene glycol separation method. On the extraction of the sera with ethanol, the concordant low values of T4 were obtained with both radioimmunoassay methods and these values were compatible with clinical findings and serum TSH levels. The thyroid hormones, thyroxine (T4) and triiodothyronine (T3), are tyrosine-based hormones produced by the thyroid gland primarily responsible for regulation of metabolism. An important component in the synthesis of thyroid hormones is iodine. The major form of thyroid hormone in the blood is thyroxine (T4), which has a longer half life than T3.

Buy ChemWhat Reagent

Want to buy this reagent? Check availability & price

Approved Bulk Manufacturers

Want to be listed as an approved manufacturer (Free service but requires approvement)? Click here to contact ChemWhat

More Suppliers

Watson International Ltd Inquiry by [email protected]
Want to be listed here as a supplier? (Paid service) Click here to contact ChemWhat

Contact Us for Other Help

Contact us for other services like technology transfer, synthetic literature, sourcing, advertisement, etc. Click here to contact ChemWhat