| Product Name |
arginine N-succinyltransferase |
| Example Structure |
 |
| Synonyms |
arginine succinyl transferase, arginine succinyltransferase, AST, AstA, More |
| EC Number |
2.3.1.109 |
| CAS Registry Number |
99676-48-9 |
| Comments |
Also acts on L-ornithine. This is the first enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine [1]. This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. The five enzymes involved in this pathway are EC 2.3.1.109 (arginine N-succinyltransferase), EC 3.5.3.23 (N-succinylarginine dihydrolase), EC 2.6.1.81 (succinylornithine transaminase), EC 1.2.1.71 (succinylglutamate-semialdehyde dehydrogenase) and EC 3.5.1.96 (succinylglutamate desuccinylase) [2,6]. |
| Cofactor |
|
| History |
|
| Reactions |
Succinyl-CoA + L-arginine = CoA + N(2)-succinyl-L-arginine. |
