aromatase EC#: 1.14.14.14; ChemWhat Code: 1375514 Product Name aromatase Example Structure Synonyms Cyp19a, CYP19A1, Cyp19a1a, Cyp19a1b, Cyp19A3, cytochrome P450 aromatase, P450arom EC Number 1.14.14.14 CAS Registry Number Comments A cytochrome P450. The enzyme catalyses three sequential hydroxylations of the androgens androst-4-ene-3,17-dione and testosterone, resulting in their aromatization and forming the estrogens estrone and 17¦Â-estradiol, respectively. Cofactor History Reactions (1) Testosterone + 3 [reduced NADPH–hemoprotein reductase] + 3 O(2) = 17-beta-estradiol + formate + 4 H(2)O + 3 [oxidized NADPH–hemoprotein reductase]. (2) Androst-4-ene-3,17-dione + 3 [reduced NADPH–hemoprotein reductase] + 3 O(2) = estrone + formate + 4 H(2)O + 3 [oxidized NADPH–hemoprotein reductase]. Buy Reagent No reagent supplier? Send quick inquiry to ChemWhat Want to be listed here as a reagent supplier? (Paid service) Click here to contact ChemWhat Approved Manufacturers Want to be listed as an approved manufacturer (Requires approvement)? Please download and fill out this form and send back to approved-manufacturers@chemwhat.com Contact Us for Other Help Contact us for other information or services Click here to contact ChemWhat
