assimilatory sulfite reductase (NADPH) EC#: 1.8.1.2; ChemWhat Code: 1374664
| Product Name | assimilatory sulfite reductase (NADPH) |
| Example Structure | ![]() |
| Synonyms | coenzyme F420-dependent sulfite reductase, CysI, CysIJ, desulforubidin, Fsr, H2S-NADP oxidoreductase, NADPH-dependent sulfite reductase, NADPH-sulfite reductase, reductase, sulfite (reduced nicotinamide adenine dinucleotide phosphate), SIR, SIR-FP, SIR-HP, SIRHP, sulfite reductase, sulfite reductase hemo-subunit |
| EC Number | 1.8.1.2 |
| CAS Registry Number | 9029-35-0 |
| Comments | Contains siroheme, [4Fe-4S] cluster, FAD and FMN. The enzyme, which catalyses the six-electron reduction of sulfite to sulfide, is involved in sulfate assimilation in bacteria and yeast. Different from EC 1.8.99.5, dissimilatory sulfite reductase, which is involved in prokaryotic sulfur-based energy metabolism. |
| Cofactor | iron-sulfur;FMN;siroheme;FAD |
| History | |
| Reactions | H(2)S + 3 NADP(+) + 3 H(2)O = sulfite + 3 Nadph. |
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