atrolysin B EC#: 3.4.24.41; ChemWhat Code: 1381028
Product Name | atrolysin B |
Example Structure | |
Synonyms | Crotalus atrox metalloendopeptidase b, Hemorrhagic toxin b, hemorrhagic toxin b metalloproteinase, HT-b |
EC Number | 3.4.24.41 |
CAS Registry Number | 172306-48-8 |
Comments | From the venom of the western diamondback rattlesnake (Crotalus atrox). In peptidase family?M12?(astacin family). |
Cofactor | Zn2+ |
History | |
Reactions | Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17 and 23-Gly-|-Phe-24 of insulin B chain; identical to the cleavage of insulin B chain by atrolysin c. Also cleaves Xaa-|-Ser bonds in glucagon. |
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