From the venom of the western diamondback rattlesnake (Crotalus atrox). In peptidase family?M12?(astacin family).
Cofactor
Zn2+
History
Reactions
Cleavage of 5-His-|-Leu-6, 10-His-|-Leu-11, 14-Ala-|-Leu-15, 16-Tyr-|-Leu-17 and 23-Gly-|-Phe-24 of insulin B chain; identical to the cleavage of insulin B chain by atrolysin c. Also cleaves Xaa-|-Ser bonds in glucagon.