aurachin B dehydrogenase EC#: 1.1.1.394; ChemWhat Code: 1373524

Product Name aurachin B dehydrogenase
Example Structure Example Structure of aurachin B dehydrogenase EC#: 1.1.1.394
Synonyms
EC Number 1.1.1.394
CAS Registry Number
Comments The enzyme from the bacterium Stigmatella aurantiaca catalyses the final step in the conversion of aurachin C to aurachin B. In vivo the enzyme catalyses the reduction of 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-1-oxide to form 2-methyl-1-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-3,4-diol (note that the reactions written above proceed from right to left), which then undergoes a spontaneous dehydration to form aurachin B.
Cofactor
History
Reactions Aurachin B + NAD(+) + H(2)O = 4-hydroxy-2-methyl-3-oxo-4-((2E,6E)- farnesyl)-3,4-dihydroquinoline 1-oxide + Nadh.

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