beta-ribofuranosylphenol 5′-phosphate synthase EC#: 2.4.2.54; ChemWhat Code: 1377815
| Product Name | beta-ribofuranosylphenol 5′-phosphate synthase |
| Example Structure |  |
| Synonyms | 4-(beta-D-ribofuranosyl)aminobenzene 5′-phosphate synthase, AF2089, beta-RFA-P synthase, beta-RFAP synthase, beta-ribofuranosylhydroxybenzene 5′-phosphate synthase, MTH0830, RFAP synthase, ribofuranosylaminobenzene 5′-phosphate synthase |
| EC Number | 2.4.2.54 |
| CAS Registry Number | |
| Comments | The enzyme is involved in biosynthesis of tetrahydromethanopterin in archaea. It was initially thought to use 4-aminobenzoate as a substrate, but was later shown to utilize 4-hydroxybenzoate [4]. The activity is dependent on Mg2+ or Mn2+ [1]. |
| Cofactor | Mn2+ or Mg2+ |
| History | |
| Reactions | 5-phospho-alpha-D-ribose 1-diphosphate + 4-hydroxybenzoate = 4-(beta-D- ribofuranosyl)phenol 5′-phosphate + CO(2) + diphosphate. |
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