biotin-[biotin carboxyl-carrier protein] ligase EC#: 6.3.4.15; ChemWhat Code: 1383837

Product Name biotin-[biotin carboxyl-carrier protein] ligase
Example Structure Example Structure of biotin-[biotin carboxyl-carrier protein] ligase EC#: 6.3.4.15
Synonyms Acetyl CoA holocarboxylase synthetase, Acetyl coenzyme A holocarboxylase synthetase, bacterial BirA biotin ligase, biotin acetyl-CoA carboxylase ligase, Biotin holoenzyme synthetase, biotin ligase, biotin protein ligase, Biotin–protein ligase, biotin-protein ligase, Biotin-[acetyl coenzyme A carboxylase] synthetase, Biotin-[acetyl-CoA carboxylase] synthetase, Biotin:apocarboxylase ligase, BirA, BirA protein, BPL, group I biotin protein ligase, HCS, Holocarboxylase synthetase, holocarboxylase synthetase 1, More, STK_15250, Synthetase, biotin-[acetyl coenzyme A carboxylase], yBL
EC Number 6.3.4.15
CAS Registry Number 37340-95-7
Comments The enzyme biotinylates a biotin carboxyl-carrier protein that is part of an acetyl-CoA carboxylase complex, enabling its subsequent carboxylation by EC?6.3.4.14, biotin carboxylase. The carboxyl group is eventually transferred to acetyl-CoA by EC?2.1.3.15, acetyl-CoA carboxytransferase. In some organisms the carrier protein is part of EC?6.4.1.2, acetyl-CoA carboxylase.
Cofactor
History
Reactions Atp + biotin + apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] = Amp + diphosphate + [acetyl-CoA:carbon-dioxide ligase (ADP-forming)].

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