| Product Name |
bisdemethoxycurcumin synthase |
| Example Structure |
 |
| Synonyms |
ClPKS10, curcuminoid synthase, CUS, Os07g0271500 |
| EC Number |
2.3.1.211 |
| CAS Registry Number |
|
| Comments |
A polyketide synthase characterized from the plant Oryza sativa (rice) that catalyses the formation of the C6-C7-C6 diarylheptanoid scaffold of bisdemethoxycurcumin. Unlike the process in the plant Curcuma longa (turmeric), where the conversion is carried out via a diketide intermediate by two different enzymes (EC 2.3.1.218, phenylpropanoyl-diketide CoA synthase and EC 2.3.1.217, curcumin synthase), the diketide intermediate formed by this enzyme remains within the enzyme’s cavity and is not released to the environment. |
| Cofactor |
|
| History |
|
| Reactions |
2 4-coumaroyl-CoA + malonyl-CoA + H(2)O = 3 CoA + bisdemethoxycurcumin + 2 CO(2). |
