C-19 steroid 1alpha-hydroxylase EC#: 1.14.15.19; ChemWhat Code: 1375709
| Product Name | C-19 steroid 1alpha-hydroxylase |
| Example Structure |  |
| Synonyms | C-19 steroid 1alpha-hydroxylase, CYP260A1 |
| EC Number | 1.14.15.19 |
| CAS Registry Number | |
| Comments | The enzyme, characterized from the bacterium Sorangium cellulosum, is a class I cytochrome P-450, and uses ferredoxin as its electron donor [1]. It was shown to act on several C-19 steroid substrates, including testosterone, androstenedione, testosterone-acetate and 11-oxoandrostenedione [2]. |
| Cofactor | |
| History | |
| Reactions | Testosterone + 2 reduced ferredoxin [iron-sulfur] cluster + O(2) + 2 H(+) = 1-alpha-hydroxytestosterone + H(2)O + 2 oxidized ferredoxin [iron- sulfur] cluster. |
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