calpain-1 EC#: 3.4.22.52; ChemWhat Code: 1380777
| Product Name | calpain-1 |
| Example Structure |  |
| Synonyms | calcium-activated neutral protease I, calpain 1, calpain 1-gamma, calpain 1A, calpain I, calpain small subunit, calpain-1, calpain-1 (micro-form), calpain-I, calpain1, CANP1, CAPN1, CAPN1 g.p. (Homo sapiens), CAPN2, CAPNS1, cysteine protease, EC 3.4.22.17, m-CANP, micro-calpain, mito-mu-calpain, mu-calpain, muCANP, muI-II |
| EC Number | 3.4.22.52 |
| CAS Registry Number | 78990-62-2 |
| Comments | In peptidase family?C2. Requires Ca2+?at micromolar concentrations for activity. Cytosolic in animal cells. The active enzyme molecule is a heterodimer in which the large subunit contains the peptidase unit, and the small subunit is also a component of EC?3.4.22.53, calpain-2. |
| Cofactor | Ca2+ |
| History | |
| Reactions | Broad endopeptidase specificity. |
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