calpain-2 EC#: 3.4.22.53; ChemWhat Code: 1380779
| Product Name | calpain-2 |
| Example Structure |  |
| Synonyms | 3.4.22.17, Cal II, calcium-activated neutral protease II, calpain 2, calpain II, calpain xCL-2 (Xenopus leavis), calpain-2, calpain-2-like, calpain2, CAPN II, CAPN2, CAPN2 g.p. (Homo sapiens), CPN2, cysteine protease, EC 3.4.22.17, human calpain 2, m-calpain, milli-calpain, mitochondrial m-calpain, nCL-2, rat calpain 2 |
| EC Number | 3.4.22.53 |
| CAS Registry Number | 78990-62-2 |
| Comments | Type example of peptidase family?C2. Requires Ca2+?at millimolar concentrations for activity. Cytosolic in animal cells. The active enzyme molecule is a heterodimer in which the large subunit contains the peptidase unit, and the small subunit is also a component of EC?3.4.22.52, calpain-1. |
| Cofactor | Ca2+ |
| History | |
| Reactions | Broad endopeptidase specificity. |
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