| Product Name |
carbamoyl-serine ammonia-lyase |
| Example Structure |
 |
| Synonyms |
ammonia-lyase, carbamoylserine, carbamoylserine deaminase, O-carbamoyl-L-serine deaminase, O-carbamoyl-L-serine deaminase (OCS) |
| EC Number |
4.3.1.13 |
| CAS Registry Number |
52227-64-2 |
| Comments |
A pyridoxal-phosphate protein. The enzyme cleaves a carbon-oxygen bond, releasing CO2, ammonia, and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and a second ammonia molecule. The latter reaction, which can occur spontaneously, can also be catalysed by EC?3.5.99.10, 2-iminobutanoate/2-iminopropanoate deaminase. |
| Cofactor |
pyridoxal 5′-phosphate |
| History |
|
| Reactions |
O-carbamoyl-L-serine + H(2)O = pyruvate + 2 NH(3) + CO(2). |
