| Product Name |
(carboxyethyl)arginine beta-lactam-synthase |
| Example Structure |
 |
| Synonyms |
beta-lactam-forming enzyme, beta-lactam-synthetase, betaLS, bls2, synthetase, beta-lactam |
| EC Number |
6.3.3.4 |
| CAS Registry Number |
|
| Comments |
Forms part of the pathway for the biosythesis of the ¦Â-lactamase inhibitor clavulanate in?Streptomyces clavuligerus. It has been proposed [3] that?L-N2-(2-carboxyethyl)arginine is first converted into an acyl-AMP by reaction with ATP and loss of diphosphate, and that the ¦Â-lactam ring is then formed by the intramolecular attack of the ¦Â-nitrogen on the activated carboxy group. |
| Cofactor |
|
| History |
|
| Reactions |
Atp + L-N(2)-(2-carboxyethyl)arginine = amp + diphosphate + deoxyamidinoproclavaminate. |