carboxypeptidase E EC#: 3.4.17.10; ChemWhat Code: 1380392

Product Name carboxypeptidase E
Example Structure Example Structure of carboxypeptidase E EC#: 3.4.17.10
Synonyms carboxypeptidase, carboxypeptidase E, carboxypeptidase E-DELTAN, carboxypeptidase E/H, carboxypeptidase H, carboxypeptidase, enkephalin precursor, Ci-CPE, cobalt stimulated chromaffin granule carboxypeptidase, CPE, CPE-DELTAN, CPH, EGL-21, enkephalin convertase, enkephalin precursor carboxypeptidase, enkephalin-precursor endopeptidase, hCPE, insulin granule-associated carboxypeptidase, MCP, membrane-bound carboxypeptidase, metallocarboxypeptidase, More, peptidyl-L-lysine(-L-arginine) hydrolase, Prohormone processing carboxypeptidase
EC Number 3.4.17.10
CAS Registry Number 81876-95-1
Comments A zinc enzyme, activated by Co2+. Inhibited by 1,10-phenanthroline and other chelating agents. pH optimum 5.6. Located in storage granules of secretory cells, and active in processing of protein hormones and bioactive peptides. In peptidase family?M14?(carboxypeptidase A family). Formerly EC?3.4.17.10, carboxypeptidase H.
Cofactor Zn2+
History
Reactions Release of C-terminal arginine or lysine residues from polypeptides.

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