cathepsin B EC#: 3.4.22.1; ChemWhat Code: 1380674
| Product Name | cathepsin B |
| Example Structure |  |
| Synonyms | AC-5, AC-cathB-1, AC-cathB-2, APP secretase, cat B, CatB, CatB1, Cath B, Cath-B, CathB, cathepsin B, cathepsin B proteinase, cathepsin B-like AC-5, cathepsin B-like counter-defence protein, cathepsin B-like cysteine protease, cathepsin B-like cysteine protease 1, cathepsin B-type cysteine protease, cathepsin B1, cathepsin B2, cathepsin II, cathepsin-B, CmCatB1, CmCatB2, CP-2, CPB, CsCB1, CsCB2, CsCB3, CsCB4, CTB, CTSB, cysteine cathepsin, DEVDase, LycCatB, MmeCB, More, Na-CP-2, Na-CP-3, Na-CP-4, Na-CP-5, nfcpb, nfcpb-L, rFgCatB2, Sm31, SmCatB, SmCB1, toxopain-1, TrCB1.1, TrCB1.2, TrCB1.3, TrCB1.4, TrCB1.5, TrCB1.6 |
| EC Number | 3.4.22.1 |
| CAS Registry Number | 9047-22-7 |
| Comments | An intracellular (lysosomal) enzyme in peptidase family?C1?(papain family). |
| Cofactor | |
| History | |
| Reactions | Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides. |
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