cathepsin F EC#: 3.4.22.41; ChemWhat Code: 1380754
| Product Name | cathepsin F |
| Example Structure |  |
| Synonyms | cat F, CatF, cathepsin f, cathepsin F-1, CATSF, CF-1, CF-11, CF-4, CF-6, cf1, CtF, CTSF, Ov-CF-1, Tci-CF-1 |
| EC Number | 3.4.22.41 |
| CAS Registry Number | |
| Comments | Cathepsin F is a lysosomal cysteine endopeptidase of family?C1?(papain family), most active at pH 5.9. The enzyme is unstable at neutral pH values and is inhibited by compound E-64. Cathepsin F is expressed in most tissues of human, mouse and rat. Human gene locus: 11q13.1-13.3. |
| Cofactor | |
| History | |
| Reactions | The recombinant enzyme cleaves synthetic substrates with Phe and Leu (better than Val) in P2, with high specificity constant (k(cat)/K(m)) comparable to that of cathepsin L. |
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